Following graduation in 1983, Flockhart attended the Mason Gross School of the Arts at Rutgers University in New Brunswick, New Jersey.
While there, she attended a specialized and competitive class, lasting from a.m. In her sophomore year at Rutgers, Flockhart met aspiring actress Jane Krakowski, the best friend of her roommate.
Rutgers inducted her into the Hall of Distinguished Alumni on May 3, 2003.
Though Flockhart at first hesitated due to the necessary commitment to the show in a negotiable contract, she was swayed by the script and traveled to Los Angeles to audition for the part, which she won.
She earned a Golden Globe Award for the role in 1998.
Flockhart also appeared on the June 29, 1998, cover of Time magazine, Flockhart performed in a starring role as Kitty Walker, opposite Sally Field, Rachel Griffiths and Matthew Rhys, in the ABC critically acclaimed prime time series Brothers & Sisters, which premiered in September 2006 in the time slot after Desperate Housewives.
The show was cancelled in May 2011 after running for five years.
Flockhart's character was significant throughout the series' first four years, but her appearances were reduced for the 2010–2011 season, coinciding with the departure of TV husband Rob Lowe.